She represented South Africa at the 2000 Sydney Olympics, with her team finishing fifth in the 4x100 medley relay. She is very interested in the sport of open water swimming and would like to lend her support to a world-class open water swim in Monaco where she can combine attention to the conservation of the world's marine environment. In 2011, she competed in the Midmar Mile and became a strong and public advocate for the sport, raising significant funds for the Special Olympics athletes, for which she was nominated for the 2011 World Open Water Swimming Woman of the Year.
Princess Charlene was a member of the South African women's 4×100 medley relay team at the 2000 Sydney Olympics, which finished fifth. She finished sixth at the 2002 FINA Short Course World Championships for the 200 backstroke. She has won several national titles over the years. She planned to compete in the 2008 Beijing Olympics, but she did not qualify.
Special Olympics ambassador
In 2011, Princess Charlene became a global ambassador for the Special Olympics.
25 January 1978 – 1 July 2011: Miss Charlene Lynette Wittstock 1 July 2011 – present: Her Serene Highness The Princess of Monaco
On her marriage, Charlene became Princess consort of Monaco and gained the title and style of Her Serene Highness The Princess of Monaco; the last to hold the title was the Prince's mother, Grace Kelly.