Dr. Lopiano was named one of "The 10 Most Powerful Women in Sports" by Fox Sports. The Sporting News has also listed her as one of "The 100 Most Influential People in Sports." She is a member of the National Sports Hall of Fame, the National Softball Hall of Fame and the Texas Women's Hall of Fame, among others. In 2003, she was inducted into the Nassau County Sports Hall of Fame.
She received her bachelor's degree from Southern Connecticut State University and her master's and doctoral degrees from the University of Southern California. She has been a college coach of men's and women's volleyball, women's basketball and softball.
As an athlete, she participated in 26 national championships in four sports and was a nine-time All-American at four different positions in softball, a sport in which she played on six national championship teams including the Connecticut Brakettes.